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 Formulary Chapter 13: Skin - Full Chapter
Notes:

Dermatology prescribing may require use of expensive unlicensed
creams and ointments (known as ‘Specials’). Please consult the revised British Association of Dermatologists (BAD) list of preferred Specials (2018) for advice on appropriate product choice.

Specials Recommended by the British Association of Dermatologists for Skin Disease

Several medicines in the skin chapter are available for purchase over the counter and may be appropriate for self care. Please consult the local OTC policy for more details.

LSCMMG: Over The Counter (OTC) Items That Should Not Be Routinely Prescribed In Primary Care Policy 

Chapter Links...
 Details...
13.01  Expand sub section  Management of skin conditions
Birch bark extract (Filsuvez Gel®)
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Formulary
Red
NHS England
BlueTeq

Gel 100mg/1g

 
Link  NICE HST28: Birch bark extract for treating epidermolysis bullosa
 
HidraWear
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Formulary
Green

 Hidradenitis Suppurativa 

 
Link  LSCMMG: HidraWear Position Statement
 
13.01.01  Expand sub section  Vehicles
13.01.02  Expand sub section  Suitable quantities for prescribing
13.01.03  Expand sub section  Excipients and sensitisation
13.02  Expand sub section  Emollient and barrier preparations to top
13.02.01  Expand sub section  Emollients
 note 

MHRA: Risk of severe and fatal burns with paraffin-containing and paraffin-free emollients

Advise patients who use these products not to smoke or go near naked flames, and warn about the easy ignition of clothing, bedding, dressings, and other fabric that have dried residue of an emollient product on them.

Emollient bath and shower preparations are no longer recommended. Most emollients can be used as a soap substitute.

Emulsifying Ointment BP
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Formulary
Green

Ointment

 
 
Epimax®
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Formulary
Green

Cream
Oatmeal cream
Ointment
Isomol gel
Excetra cream

Do not prescribe Epimax® ointment for use on the face. 

 
Link  MHRA: Epimax Ointment and Epimax Paraffin-Free Ointment: reports of ocular surface toxicity and ocular chemical injury
 
Hydromol
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Formulary
Green

Ointment

 
 
Liquid and White Soft Paraffin Ointment (50:50)
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Formulary
Green

Ointment

 
 
Oilatum®
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Formulary
Green

Cream

 
 
ZeroAQS®
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Formulary
Green

Aqueous cream, sodium lauryl sulfate free.

 
 
13.02.01  Expand sub section  Emollients - with antimicrobials
Dermol®
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Formulary
Green

Cream
Lotion

Contains antimicrobials.

 
 
13.02.01  Expand sub section  Preparations containing urea
Balneum® plus
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Formulary
Green Restricted

Cream

Prescribing restricted to the treatment of CKD-associated Pruritus, in line with the Enhanced Supportive Kidney Care Guideline.

 
 
Emollients containing urea
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Formulary

Green Cream 10% (Flexitol®)

Green Cream 10% (Hydromol® Intensive)

Green Restricted Heel balm 25% (Flexitol®) - Use restricted to diabetic patient's only

 
 
ImuDERM®
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Formulary
Green

Emollient 5%

 
 
13.02.01.01  Expand sub section  Emollient bath and shower preparations
13.02.02  Expand sub section  Barrier preparations to top
Conotrane®
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Formulary
Green

Cream

 
 
Medi Derma-S
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Formulary
Green

Spray barrier film

 
 
Metanium®
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Formulary
Green

Ointment

Paediatric use only.
Tissue viability nurse authorisation required for use in adult patients.

 
 
Proshield Plus®
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Formulary
Green

Ointment

For excoriated skin.

 
 
Sorbaderm®
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Formulary
Green

Cream

 
 
Sudocrem®
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Formulary
Green

Cream

For paediatric use only.

 
 
13.03  Expand sub section  Topical local anaesthetics and antipruritics
 note 

Also see chapter 15.02 Local anaesthesia.

Crotamiton (Eurax®)
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Formulary
Green

Cream 10%

 
 
Levomenthol
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Formulary
Green

Cream 0.5%, 1%, 2%, 5%

 
 
Difelikefalin Black Triangle (Kapruvia®)
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Formulary
Red
NHS England
BlueTeq

Solution for injection 50micrograms/mL

Under expert supervision.

 
Link  NICE TA890: Difelikefalin for treating pruritus in people having haemodialysis
 
13.04  Expand sub section  Topical corticosteroids.
 note 

In the BNF publications topical corticosteroids for the skin are categorised as ‘mild’, ‘moderately potent’, ‘potent’ or ‘very potent’; the least potent preparation which is effective should be chosen but dilution should be avoided whenever possible.

Potency of a topical corticosteroid preparation (including compound preparations) is based solely on the corticosteroid component, irrespective of the formulation and strength.

The potency of each topical corticosteroid should be included on the label with the directions for use. The label should be attached to the container (for example, the tube) rather than the outer packaging.

For guidance on quantities to prescribe see BNF:
https://bnf.nice.org.uk/treatment-summaries/topical-corticosteroids/

Hydrocortisone
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Formulary
Green

Cream 1%
Ointment 1%

Consider OTC/Self care.

Mild corticosteroid.

 
 
Hydrocortisone with clotrimazole (Canesten HC®)
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Formulary
Green

Cream hydrocortisone 1%, clotrimazole 1% 

Consider OTC/Self care.

Mild corticosteroid.

 
 
Hydrocortisone with fusidic acid (Fucidin H®)
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Formulary
Green

Cream hydrocortisone acetate 1%, fusidic Acid 2%

Preparations containing fusidic acid should not be used in secondary care for in-patients.

Mild corticosteroid.

 
 
Hydrocortisone with benzalkonium chloride, dimeticone and nystatin (Timodine®)
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Formulary
Green

Cream hydrocortisone 0.5%, nystatin 100000 unit per 1 g, benzalkonium chloride 0.2%, dimeticone '350' 10% 

Mild corticosteroid.

 
 
Hydrocortisone butyrate (Locoid®)
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Formulary
Amber 0
Lipocream 0.1%
 
Lichen sclerosus in women when betamethasone cream is ineffective.

Moderate corticosteroid.
 
 
Clobetasone Butyrate
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Formulary
Green

Cream 0.05% (Eumovate®)
Ointment 0.05%

Moderate corticosteroid.

 
 
Clobetasone butyrate with nystatin and oxytetracycline (Trimovate®)
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Formulary
Green

Cream clobetasone 0.05%, nystatin 100000 unit per 1 gram, oxytetracycline 3%

Moderate corticosteroid.

 
 
Betamethasone Valerate
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Formulary
Green

Cream 0.025%, 0.1%
Ointment 0.025%, 0.1%
Scalp application 0.1%
Foam 0.1% (Bettamousse®)

Potent corticosteroid.

 
 
Betamethasone dipropionate with salicylic acid (Diprosalic®)
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Formulary
Green

Ointment betamethasone 0.05%, salicylic acid 3%
Scalp application betamethasone 0.05%, salicylic acid 2%

Potent corticosteroid.

 
 
Betamethasone valerate with fusidic acid
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Formulary
Green

Cream betamethasone 0.1%, fusidic acid 2%

Preparations containing fusidic acid should not be used in secondary care for in-patients.

Potent corticosteroid.

 
 
Betamethasone dipropionate with clotrimazole (Lotriderm®)
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Formulary
Green

Cream betamethasone 0.064% , clotrimazole 1%

Potent corticosteroid.

 
 
Flucinolone Acetonide
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Formulary
Green

Gel 0.025% (Synalar®)

For scalp use only.

Potent corticosteroid.

 
 
Fludroxycortide
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Formulary
Green

Tape 4micrograms/square cm,  7.5cm

Potent corticosteroid.

 
 
Mometasone Furoate
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Formulary
Amber 0

Cream 0.1%
Ointment 0.1%

Potent corticosteroid.

 
 
Clobetasol Propionate
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Formulary

Green Cream 0.05%, Ointment 0.05%
Green Cutaneous foam 0.05% (Clarelux®)
Amber 0 Shampoo 0.05% (Etrivex®)

Very potent corticosteroid.

 
 
Betamethasone dipropionate (Diprosone®)
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Formulary
Red

Cream 0.05%

For use post urology surgery.

Potent corticosteroid.

 
 
13.04  Expand sub section  Topical corticosteriod preparation potencies
13.04  Expand sub section  Topical corticosteroids (Potency: Mild)
13.04  Expand sub section  Topical corticosteroids (Potency: Moderate) to top
13.04  Expand sub section  Topical corticosteroids (Potency: Potent)
13.04  Expand sub section  Topical corticosteroids (Potency: Very Potent)
13.04.01  Expand sub section  Topical corticosteroids – Compound preparations – with antimicrobials
13.04.01  Expand sub section  Topical corticosteroids – Compound preparations – with salicyclic acid
13.05  Expand sub section  Preparations for eczema and psoriasis to top
13.05.01  Expand sub section  Preparations for eczema
Alitretinoin (Prescribe generically)
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Formulary
Red
High Cost Medicine
BlueTeq

Capsules 10mg, 30mg

Prescribed by or under supervision of a consultant dermatologist.

Healthcare professionals are reminded that the use of oral retinoids is contra-indicated in pregnancy due to a high risk of serious congenital malformations, and any use in females must be within the conditions of the Pregnancy Prevention Programme.


MHRA: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women


Each prescription for oral alitretinoin should be limited to a supply of up to 28 days treatment. Pregnancy must be excluded before initiation and before each repeat prescription.

Contra-indicated in patients with hypersensitivity to peanuts or soya (capsule filling contains soya-bean oil).

Neuropsychiatric reactions have been reported in patients taking oral retinoids. The MHRA advises patients and carers to seek medical attention if changes in mood or behaviour occur.

Patients should avoid excessive exposure to UV light (including sunlight, solariums)—sunscreen with a high protection factor should be applied.

 
Link  MHRA: Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk
Link  NICE TA177: Alitretinoin for the treatment of severe chronic hand eczema
 
Ichthammol with zinc oxide
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Formulary

Green Bandage 7.5cm x 6m (Ichthopaste®)
Amber 0 Ointment zinc oxide 15% and ichthammol 1% in yellow soft paraffin (Special ointment No1) unlicensed

 
 
Zinc Oxide
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Formulary
Green

Bandage 7.5cm x 6m (Viscopaste®)

 
 
13.05.01  Expand sub section  Topical preparations for eczema
13.05.02  Expand sub section  Preparations for psoriasis
Dimethyl Fumarate (Skilarence®)
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Formulary
Red
BlueTeq

Tablets 30mg, 120mg

The MHRA recommends that patients and their carers should be counselled on the risk of progressive multifocal leukoencephalopathy and advised to seek immediate medical attention if symptoms develop.

 
Link  NICE TA475: Dimethyl fumarate for treating moderate to severe plaque psoriasis
 
Ixekizumab  (Taltz®)
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Formulary
Red
High Cost Medicine
CCG
BlueTeq

Injection pre-filled pen 80mg/1ml
Injection pre-filled syringe 80mg/1ml

Under expert supervision.

 
Link  NICE TA442: Ixekizumab for treating moderate to severe plaque psoriasis
Link  NICE TA537: Ixekizumab for treating active psoriatic arthritis after inadequate response to DMARDs
 
SpesolimabBlack Triangle (Spevigo®)
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Formulary
Red
High Cost Medicine
BlueTeq

Solution for infusion 450mg/7.5ml

Under expert supervision.

 
Link  NICE TA1070: Spesolimab for treating generalised pustular psoriasis flares
 
Methoxypsoralen
Unlicensed Drug Unlicensed
Red
Bath lotion 1.2%
Gel 0.005%
Tablets 10mg 
 
13.05.02  Expand sub section  Topical preparations for psoriasis
Tacalcitol (Curatoderm®)
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Formulary
Green

Ointment 4micrograms/g

 
 
Calcipotriol
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Formulary
Green

Ointment 50micrograms/g

 
 
Calcipotriol with betamethasone
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Formulary
Green

Gel calcipotriol 0.005%, betamethasone dipropionate 0.05%
Cutaneous foam calcipotriol 0.005%, betamethasone dipropionate 0.05% (Enstilar®)

Potent corticosteroid.

 
 
Coal tar
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Formulary

Green Lotion - Coal tar 5% (Exorex®)
Green Scalp Ointment - Coal tar 1%, salicylic acid 2%, precipitated sulfur 4% (Sebco®)
Amber 0  Ointment BP - Coal tar 2%, salicylic acid 2% unlicensed  - For scalp use only
Amber 0 Ointment - Coal tar, emulsifying ointment unlicensed 

Not all coal tar products are routinely stocked by pharmacy departments. If the product has to be obtained from a specials manufacturing unit there may be a delay of up to 4 weeks.

 
 
Salicylic acid with zinc oxide (Lassars Paste)
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Formulary
Amber 0

Paste zinc oxide 24%, salicylic acid 2%, starch 24%, white soft paraffin 50%

 
 
Salicylic acid in emulsifying ointment
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Formulary
Red

Ointment 2%, 5%, 10%

unlicensed 

 
 
Dithranol in Lassar’s Paste
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Unlicensed Drug Unlicensed
Amber 0

10%
(0.1%, 0.25%, 0.5%, 1%, 2%, 4%, 6%, 8% dilutions available from pharmacy)
Not all dithranol products are routinely stocked by the pharmacy departments. If the product has to be obtained from a specials manufacturing unit there may be a delay for up to 4 weeks.

 
 
13.05.02  Expand sub section  Oral retinoids for psoriasis to top
Acitretin (Neotigason®)
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Formulary
Red

Capsules 10mg, 25mg

Prescribed by or under supervision of a consultant dermatologist.

Healthcare professionals are reminded that the use of oral retinoids is contra-indicated in pregnancy due to a high risk of serious congenital malformations, and any use in females must be within the conditions of the Pregnancy Prevention Programme.


MHRA: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women


Each prescription for oral acitretin should be limited to a supply of up to 28 days treatment. Pregnancy must be excluded before initiation and before each repeat prescription.

Neuropsychiatric reactions have been reported in patients taking oral retinoids. The MHRA advises patients and carers to seek medical attention if changes in mood or behaviour occur.

 
Link  MHRA: Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk
 
13.05.03  Expand sub section  Drugs affecting the immune response
 note 

Consultant dermatologist or specialist initiation only.
To be prescribed in accordance with local and NICE guidance.

Medicines are commissioned by NHS England for paediatric indications where an adult NICE TA is in place.

AbrocitinibBlack Triangle (Cibinqo ®)
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Formulary
Red
BlueTeq

Tablets 50mg, 100mg, 200mg

 
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  NICE TA814: Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis
 
Adalimumab
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Formulary
Red
Homecare
BlueTeq

S/C injection 40mg pre-filled syringe, pre-filled pen

Tertiary centre only for hidradenitis suppurativa.

Commissioned in accordance with LSCMMG biologics pathways.
NHSE commissioned for some indications.
Consult chapter links for more details.

 
Link  MHRA: Tumour necrosis factor alpha inhibitors
Link  NICE TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis
Link  NICE TA392: Adalimumab for treating moderate to severe hidradenitis suppurativa
Link  NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
Link  NIE TA146: Adalimumab for the treatment of adults with psoriasis
 
Apremilast (Otezla®)
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Formulary
Red
Homecare
BlueTeq

Tablets 10mg, 20mg, 30mg

 
Link  MHRA: Apremilast (Otezla ▼): risk of suicidal thoughts and behaviour
Link  NICE TA419: Apremilast for treating moderate to severe plaque psoriasis
Link  NICE TA433: Apremilast for treating active psoriatic arthritis
 
Cytotoxic Drug Azathioprine
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Formulary
Amber 2

Tablets 25mg, 50mg

Some indications are unlicensed unlicensed. Please consult product literature for licensing information.

Consultant dermatologist or specialist initiation only.

 
Link  LSCMMG: Azathioprine and Mercaptopurine shared care guideline
Link  MHRA: Thiopurines and intrahepatic cholestasis of pregnancy
 
Baricitinib
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Formulary
BlueTeq

Film-coated tablets 2mg, 4mg

Red Treatment of atopic dermatitis

Do Not Prescribe Treatment of alopecia areata

 
Link  MHRA: Baricitinib (Olumiant▼): increased risk of diverticulitis, particularly in patients with risk factors
Link  MHRA: Baricitinib (Olumiant▼): risk of venous thromboembolism
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  NICE TA681: Baricitinib for treating moderate to severe atopic dermatitis
Link  NICE TA926: Baricitinib for treating severe alopecia areata
 
BimekizumabBlack Triangle (Bimzelx ®)
View adult BNF View SPC online View SMC online View childrens BNF
Formulary
Red
Homecare
BlueTeq

Solution for injection pre-filled pen 160mg/1ml, 320mg/2ml
Solution for injection pre-filled syringe 160mg/1ml, 320mg/2ml

 
Link  NICE TA723: Bimekizumab for treating moderate to severe plaque psoriasis
Link  NICE TA916: Bimekizumab for treating active psoriatic arthritis
 
Brodalumab (Kyntheum®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled syringes 210mg/1.5ml 

 
Link  NICE TA511: Brodalumab for treating moderate to severe plaque psoriasis
 
Certolizumab pegol (Cimzia®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled pens 200mg/1ml
Solution for injection pre-filled syringes 200mg/1ml
Solution for injection in a dose-dispenser cartridge 200mg/1ml

Commissioned in accordance with LSCMMG biologics pathways.
Consult chapter links for more details.

 
Link  MHRA: Tumour necrosis factor alpha inhibitors
Link  NICE TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs
Link  NICE TA574: Certolizumab pegol for treating moderate to severe plaque psoriasis
 
Ciclosporin
View adult BNF View SPC online View childrens BNF
Formulary
Amber 2

Capsules 10mg, 25mg, 50mg, 100mg
Oral solution 100mg/ml

Consultant dermatologist or specilaist initiation only.

Patients should be stabilised on a particular brand of oral ciclosporin because switching between formulations without close monitoring may lead to clinically important changes in blood-ciclosporin concentration.

 
Link  LSCMMG: Ciclosporin shared care guideline
 
DeucravacitinibBlack Triangle (Sotyktu®)
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Formulary
Red
BlueTeq

Film coated tablets 6mg

It is not known whether deucravacitinib, an inhibitor of tyrosine kinase 2 (TYK2), is associated with the adverse reactions of Janus kinase (JAK) inhibition. Risks that have been identified as a class effect of JAK inhibitors include major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality.  

 
Link  NICE TA907: Deucravacitinib for treating moderate to severe plaque psoriasis
 
Dupilumab (Dupixent®)
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Formulary
Red
Homecare
BlueTeq

Solution for injection pre-filled pens 300mg/2ml, 200mg/1.14ml
Solution for injection pre-filled syringes 300mg/2ml, 200mg/1.14ml

Do Not Prescribe NICE TA955: Dupilumab for treating moderate to severe prurigo nodularis

 
Link  MHRA: Dupilumab (Dupixent▼): risk of ocular adverse reactions and need for prompt management
Link  NICE TA534: Dupilumab for treating moderate to severe atopic dermatitis
Link  NICE TA955: Dupilumab for treating moderate to severe prurigo nodularis
 
Etanercept
View adult BNF View SPC online View childrens BNF
Formulary
Red
Homecare
BlueTeq

S/C injection 50mg pre-filled syringe, pre-filled pen

 
Link  MHRA: Tumour necrosis factor alpha inhibitors
Link  NICE TA103: Etanercept and efalizumab for the treatment of adults with psoriasis
Link  NICE TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis
Link  NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
 
Guselkumab (Tremfya®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
Homecare
BlueTeq

Solution for injection in pre-filled pen 100mg/1ml

 
Link  NICE TA521: Guselkumab for treating moderate to severe plaque psoriasis
Link  NICE TA815: Guselkumab for treating active psoriatic arthritis after inadequate response to DMARDs
 
Infliximab
View adult BNF View SPC online View childrens BNF
Formulary
Red
BlueTeq

Solution for injection pre-filled pen 120 mg/1ml 

Adequate resuscitation facilities must be available when infliximab is used.

 
Link  MHRA: Tumour necrosis factor alpha inhibitors
Link  NICE TA134: Infliximab for the treatment of adults with psoriasis
Link  NICE TA199: Etanercept, infliximab and adalimumab for the treatment of psoriatic arthritis
 
LebrikizumabBlack Triangle (Ebglyss®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled pens 250mg/2ml
Solution for injection pre-filled syringes 250mg/2ml

The MHRA has reviewed the risk of dry eye and serious ocular side-effects associated with dupilumab, an inhibitor of interleukin-4 and interleukin-13 signalling. Lebrikizumab, which similarly inhibits interleukin-13, is also associated with ocular side-effects.

 
Link  MHRA: Dupilumab (Dupixent▼): risk of ocular adverse reactions and need for prompt management
Link  NICE TA986: Lebrikizumab for treating moderate to severe atopic dermatitis in people 12 years and over
 
Cytotoxic Drug Methotrexate
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Formulary
Amber 2
Homecare

Tablets 2.5mg
Prefilled syringes and pens (various strengths)

Methotrexate should be prescribed once weekly as a single dose on the same day each week.
If oral methotrexate is prescribed only use the 2.5 mg strength.
See hospital policy for prescribing and supply of oral methotrexate.

Methotrexate subcutaneous injection may be supplied through a homecare arrangement.

 
Link  LSCMMG: Methotrexate shared care guideline
Link  MHRA: Methotrexate once-weekly for autoimmune diseases: new measures to reduce risk of fatal overdose due to inadvertent daily instead of weekly dosing
Link  MHRA: Methotrexate: advise patients to take precautions in the sun to avoid photosensitivity reactions
 
NemolizumabBlack Triangle (Nemluvio®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
NHS England
BlueTeq

30 mg powder and solvent for solution for injection in pre-filled pen

 
Link  NICE TA1077: Nemolizumab for treating moderate to severe atopic dermatitis in people 12 years and over
 
Omalizumab (Xolair®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled pens 75mg/0.5ml, 150mg/1ml, 300mg/2ml
Solution for injection pre-filled syringes 75mg/0.5ml, 150mg/1ml, 300mg/2ml

unlicensed Unlicensed use of omalizumab for severe chronic inducible urticarias.

 
Link  LSCMMG: Commissioning statement Unlicensed use of omalizumab for severe chronic inducible urticarias
Link  MHRA: Omalizumab: potential risk of arterial thrombotic events
Link  NICE TA339: Omalizumab for previously treated chronic spontaneous urticaria
 
Pimecrolimus (Elidel®)
View adult BNF View SPC online View childrens BNF
Formulary
Amber 0

Cream 1% 

Consultant dermatologist or specilaist initiation only.

 
Link  NICE TA82: Tacrolimus and pimecrolimus for atopic eczema
 
Risankizumab (Skyrizi®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled syringes 150mg/mL
Solution for injection pre-filled pen 150mg/mL
Solution for injection cartridges 180mg/1.2ml, 360mg/2.4ml

 
Link  NICE TA596: Risankizumab for treating moderate to severe plaque psoriasis
Link  NICE TA803: Risankizumab for treating active psoriatic arthritis after inadequate response to DMARDs
 
RitlecitinibBlack Triangle (Litfulo®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
BlueTeq

Capsules 50mg

 
Link  BAD: Professional guidance supplementary to NICE TA958
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  NICE TA958: Ritlecitinib for treating severe alopecia areata in people 12 years and over
 
Secukinumab (Cosentyx®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
Homecare
BlueTeq

Solution for injection pre-filled pens 150mg/1ml, 300mg/2ml
Solution for injection pre-filled syringes 75mg/0.5ml, 150mg/1ml

NHSE NHSE commissioned for some indications.

Approved by LSCMMG for palmoplantar psoriasis unlicensed

 
Link  LSCMMG: Secukinumab (Cosentyx▼) NMR
Link  NICE TA350: Secukinumab for treating moderate to severe plaque psoriasis
Link  NICE TA445: Certolizumab pegol and secukinumab for treating active psoriatic arthritis after inadequate response to DMARDs
Link  NICE TA734: Secukinumab for treating moderate to severe plaque psoriasis in children and young people
Link  NICE TA935: Secukinumab for treating moderate to severe hidradenitis suppurativa
 
Tacrolimus
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Formulary
Amber 0

Ointment 0.03%, 0.1%

Psoriasis.

Consultant dermatologist or specilaist initiation only.

 
Link  MHRA: Tacrolimus ointment (Protopic): possible risk of malignancies including lymphomas and skin cancers
Link  NICE TA82: Tacrolimus and pimecrolimus for atopic eczema
 
Tildrakizumab (Ilumetri®)
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Formulary
Red
BlueTeq

Solution for injection pre-filled syringes 100mg/1ml

 
Link  NICE TA575: Tildrakizumab for treating moderate to severe plaque psoriasis
 
TralokinumabBlack Triangle (Adtralza ®)
View adult BNF View SPC online View childrens BNF
Formulary
Red
BlueTeq

Solution for injection pre-filled syringes 150mg/1ml
Solution for injection pre-filled pens 300mg/2ml

The MHRA has reviewed the risk of dry eye and serious ocular side-effects associated with dupilumab, an inhibitor of interleukin-4 and interleukin-13 signalling. Tralokinumab, which similarly inhibits interleukin-13, is also associated with ocular side-effects.

 
Link  MHRA: Dupilumab (Dupixent▼): risk of ocular adverse reactions and need for prompt management
Link  NICE TA814: Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis
 
Upadacitinib  (Rinvoq ®)
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Formulary
Red
Homecare
BlueTeq

Prolonged release tablets 15mg, 30mg, 45mg

 
Link  MHRA: Janus kinase (JAK) inhibitors: new measures to reduce risks of major cardiovascular events, malignancy, venous thromboembolism, serious infections and increased mortality
Link  NICE TA814: Abrocitinib, tralokinumab or upadacitinib for treating moderate to severe atopic dermatitis
Link  NICE768: Upadacitinib for treating active psoriatic arthritis after inadequate response to DMARDs
 
Ustekinumab
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Formulary
Red
Homecare
BlueTeq

Solution for injection pre-filled syringes 45mg/0.5ml, 90mg/1ml

Consultant dermatologist or specialist initiation only.

 
Link  MHRA: Ustekinumab (Stelara): risk of exfoliative dermatitis
Link  NICE TA180: Ustekinumab for the treatment of adults with moderate to severe psoriasis
Link  NICE TA340: Ustekinumab for treating active psoriatic arthritis
Link  NICE TA455: Adalimumab, etanercept and ustekinumab for treating plaque psoriasis in children and young people
 
13.06  Expand sub section  Acne and rosacea
Brimonidine tartrate (Mirvaso® )
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Formulary
Green Restricted

Gel 3mg/g

Restricted to use in patients with moderate to severe, persistent facial erythema of rosacea.

 
Link  LSCMMG: Brimonidine Tartrate (Mirvaso) 3mg/g Gel NMR
Link  MHRA: Brimonidine gel (Mirvaso): risk of exacerbation of rosacea
Link  MHRA: Brimonidine gel (Mirvaso): risk of systemic cardiovascular effects; not to be applied to damaged skin
 
Ivermectin
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Formulary
Green
Cream 10mg/g
 
Topical treatment of inflammatory lesions of rosacea (papulopustular) in adults.
 
Appropriate for initiation and on-going prescribing in both primary and secondary care. To be used as an alternative treatment when metronidazole and azelaic acid topical preparations are not effective, contraindicated or not tolerated by the patient. Ivermectin cream may be tried for a 3 month period, at which point it can be stopped if not effective or continued if effective.
 
For indications relating to oral ivermectin see subsection 05.05 Anthelmintics.
 
Link  LSCMMG: Ivermectin cream 10mg/g (Soolantra®) NMR
 
13.06.01  Expand sub section  Topical preparations for acne
13.06.01  Expand sub section  Benzoyl peroxide and azelaic acid
Azelaic Acid
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Formulary
Green

Gel 15% (Finacae®)
Cream 20% (Skinoren®)

 
 
Benzoyl Peroxide (Acnecide®)
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Formulary
Green

Gel 5%

If sun exposure is unavoidable, an appropriate sunscreen or protective clothing should be used.

 
 
Benzoyl peroxide with clindamycin
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Formulary
Green

Gel benzoyl peroxide 5%, clindamycin 1% 

If sun exposure is unavoidable, an appropriate sunscreen or protective clothing should be used.

 
 
13.06.01  Expand sub section  Topical antibacterials for acne to top
Erythromycin with zinc acetate
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Formulary
Green

Lotion erythromycin 40mg/ml, zinc acetate 12mg/ml

 
 
Clindamycin
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Formulary
Green

Lotion 1%
Gel 1% (Zindaclin®)

 
 
13.06.01  Expand sub section  Topical retinoids and related preparations for acne
 note 

If sun exposure is unavoidable, an appropriate sunscreen or protective clothing should be used.

Adapalene (Differin®)
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Formulary
Green

Cream 0.1%
Gel 0.1%

The MHRA advises females of childbearing potential should use effective contraception.

Contraindicated during pregnancy.

 
 
Adapalene with benzoyl peroxide
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Formulary
Green

Gel adapalene 0.1%, benzoyl peroxide 2.5% 

The MHRA advises females of childbearing potential should use effective contraception.

Contraindicated during pregnancy.

 
 
Tretinoin with clindamycin (Treclin®)
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Formulary
Green

Gel clindamycin 1%, tretinoin 0.025%

The MHRA advises females of childbearing potential should use effective contraception.

Contraindicated during pregnancy.

 
 
TrifaroteneBlack Triangle (Aklief®)
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Formulary
Green

Cream 50micrograms/g

Acne vulgaris of the face and/or the trunk in patients from 12 years of age and older, when many comedones, papules and pustules are present.

The MHRA advises females of childbearing potential should use effective contraception.

Contraindicated during pregnancy.

 
Link  LSCMMG: Trifarotene (Aklief®) 50 microgram/g cream NMR
 
13.06.01  Expand sub section  Other topical preparations for acne
13.06.02  Expand sub section  Oral preparations for acne
13.06.02  Expand sub section  Oral antibiotics for acne
Doxycycline
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Formulary
Green

Capsules 50mg, 100mg
Dispersible tablets 100mg

 
 
Erythromycin
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Formulary
Green

Tablets e/c 250mg
Suspension 125mg/5mL, 250mg/5mL

 
Link  MHRA: Erythromycin: caution required due to cardiac risks (QT interval prolongation); drug interaction with rivaroxaban
Link  MHRA: Erythromycin: update on known risk of infantile hypertrophic pyloric stenosis
 
Lymecycline
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Formulary
Green
Capsules 408mg 
 
Oxytetracycline
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Formulary
Green
Tablets 250mg 
 
13.06.02  Expand sub section  Hormone treatment for acne to top
Co-Cyprindiol
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Formulary
Green

Tablets cyproterone 2mg / ethinylestradiol 35 micrograms

 
Link  MHRA: Cyproterone acetate with ethinylestradiol (co-cyprindiol): balance of benefits and risks remains positive
Link  MHRA: Cyproterone acetate: new advice to minimise risk of meningioma
 
13.06.02  Expand sub section  Oral retinoid for acne
IsotretinoinBlack Triangle
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Formulary
Red

Capsules 5mg, 10mg, 20mg

Consultant dermatologist or specialist only.

Healthcare professionals are reminded that the use of oral retinoids is contra-indicated in pregnancy due to a high risk of serious congenital malformations, and any use in females must be within the conditions of the Pregnancy Prevention Programme.


MHRA: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women


Each prescription for oral isotretinoin for women should be limited to a supply of up to 28 days' treatment. Pregnancy must be excluded before initiation and before each repeat prescription.

As a RED drug, isotretinoin should be supplied by secondary care. Local exceptions to this are for patients under the care of the consultant-led integrated community dermatology service, OMNES.  

 Community pharmacies can dispense FP10s for isotretinoin from OMNES where it is clear that the prescription has been issued within the context of a Pregnancy Prevention Programme. Do not dispense 7 days beyond issue date of FP10. Please refer the pharmacy checklist and  Isotretinoin (Roaccutane): introduction of new safety measures, including additional oversight of the initiation of treatment for patients under 18 years of age 

Contra-indicated in patients with hypersensitivity to peanuts or soya (capsule filling contains soya-bean oil).

Neuropsychiatric reactions have been reported in patients taking oral retinoids. The MHRA advises patients and carers to seek medical attention if changes in mood or behaviour occur.

Patients should avoid excessive exposure to UV light (including sunlight, solariums)—sunscreen with a high protection factor should be applied.

 
Link  MHRA: Isotretinoin (Roaccutane▼): introduction of new safety measures, including additional oversight of the initiation of treatment for patients under 18 years of age
Link  MHRA: Isotretinoin: risk of serious skin reactions
Link  MHRA: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women
Link  MHRA: Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk
 
13.06.03  Expand sub section  Topical preparations for rosacea
13.07  Expand sub section  Preparations for warts and calluses
Salicylic acid with lactic acid
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Formulary
Green

Paint 10mL

 
 
Salicylic Acid
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Formulary
Green

Solution 26%

 
 
Silver Nitrate (Avoca®)
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Formulary

Caustic applicator 75%

Green for Warts
Red for over-granulating wounds

 
 
13.07  Expand sub section  Anogenital warts
Imiquimod (Aldara®)
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Formulary
Amber 0

Cream 5%

External genital warts.

 
 
Podophyllotoxin (Warticon®)
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Formulary
Green

Cream 0.15%
Solution 0.5%

 
 
13.08  Expand sub section  Sunscreens and camouflagers to top
13.08.01  Expand sub section  Sunscreen preparations
 note 

Some sunscreen products have ACBS approval. They may be prescribed for skin protection against ultraviolet radiation and/or visible light in abnormal cutaneous photosensitivity causing severe cutaneous reactions in genetic disorders (including xeroderma pigmentosum and porphyrias), severe photodermatoses (both idiopathic and acquired) and in those with increased risk of ultraviolet radiation causing adverse effects due to chronic disease (such as haematological malignancies), medical therapies and/or procedures.

Anthelios®
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Formulary
Green

Sunscreen Lotion SPF 50+

For ACBS conditions only, otherwise self care.

 
 
Uvistat®
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Formulary
Green
Lipscreen SPF 50, Suncream SPF 30, and Suncream SPF 50.
 
For ACBS conditions only, otherwise self care.
 
 
13.08.01  Expand sub section  Photodamage
Diclofenac
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Formulary
Green

Gel 3%

 
 
TirbanibulinBlack Triangle (Klisyri ®)
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Formulary
Green

Ointment 10 mg/g

 
 
Cytotoxic Drug Fluorouracil (Efudix®)
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Formulary

Cream 5%

Green Treatment of superficial pre-malignant skin lesions (e.g. actinic keratosis) - Prescribers should refer patients with skin lesions suggestive of skin cancers using the principles of the NICE suspected cancer guideline. Patients must be counselled in full on the correct use of fluorouracil 5% Cream, its risks and side effects.
Red Treatment of small superficial basal-cell carcinomas in adults - Only to be prescribed by skin cancer specialists or a suitably qualified GP with specialist interest (GPwSI) with demonstrable clinical skills and competencies, training and experience.

 
Link  LSCMMG: Fluorouracil 5% Cream NMR
Link  LSCMMG: Imiquimod cream (Aldara) and fluorouracil cream (Efudix) NMR
 
Cytotoxic Drug Fluorouracil (Tolak®)
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Formulary
Green
Cream 4%
 
For treatment of non-hyperkeratotic, non-hypertrophic actinic keratosis (Olsen grade I and II) of the face, ears, and/or scalp in adults.
Prescribers should refer patients with skin lesions suggestive of skin cancers using the principles of the NICE suspected cancer guideline. Patients must be counselled in full on the correct use of fluorouracil 4% Cream, its risks and side effects.
 
 
Aminolevulinic acid  (Ameluz®)
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Formulary
Red

Gel 78mg/g

 
 
Imiquimod
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Formulary

Amber 0 Cream 5% (Aldara®) Treatment of actinic keratosis
Red Cream 5% (Aldara®) Treatment of small superficial basal-cell carcinomas in adults - Only to be prescribed by skin cancer specialists or a suitably qualified GP with specialist interest (GPwSI) with demonstrable clinical skills and competencies, training and experience.
Do Not Prescribe Cream 3.75% (Zyclara®) Treatment of Actinic Keratosis
ial basal cell carcinoma in adults

 
Link  LSCMMG: Imiquimod cream (Aldara) and fluorouracil cream (Efudix) NMR
 
Methyl-5-Aminolevulinate (Metvix®)
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Formulary
Red

Cream 160 mg/g

 
 
Fluorouracil with salicylic acid (Actikerall®)
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Formulary
Do Not Prescribe

Solution fluorouracil 0.5%, salicylic acid 10%

 
 
13.08.02  Expand sub section  Camouflagers
Ruxolitinib cream
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Formulary
Do Not Prescribe

For treating non-segmental vitiligo in people 12 years and over

 
Link  NICE TA1088: Ruxolitinib cream for treating non-segmental vitiligo in people 12 years and over
 
13.09  Expand sub section  Shampoos and other preparations for scalp and hair conditions
Coal Tar
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Formulary
Green

Shampoo

Consider OTC/Self care.

 
 
Coal tar with coconut oil and salicylic acid (Capasal®)
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Formulary
Green

Shampoo coal tar distilled 10mg per 1gram, Coconut oil 10mg per 1gram, Salicylic acid 5mg per 1gram

Consider OTC/Self care.

 
 
Ketoconazole
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Formulary
Green

Shampoo 2%

Consider OTC/Self care.

 
 
13.09  Expand sub section  Hirsutism to top
Eflornithine (Vaniqa®)
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Formulary
Do Not Prescribe
 
Link  LSCMMG: Eflornithine (Vaniqa®) NMR
 
13.09  Expand sub section  Androgenetic alopecia
13.10  Expand sub section  Anti-infective skin preparations
13.10.01  Expand sub section  Antibacterial preparations
13.10.01.01  Expand sub section  Antibacterial preparations only used topically
Mupirocin (Bactroban®)
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Formulary
Green

Cream 2%

 
 
Silver sulfadiazine (Flamazine®)
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Formulary
Green

Cream 1%

 
 
13.10.01.02  Expand sub section  Antibacterial preparations also used systemically to top
Fusidic acid (Sodium fusidate)
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Formulary
Green

Cream 2%
Ointment 2%

To avoid the development of resistance, fusidic acid should not be used for longer than 10 days and local microbiology advice should be sought before using it in hospital.

 
 
Metronidazole
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Formulary
Green

Gel 0.75%

Cream 0.75%

 
 
13.10.02  Expand sub section  Antifungal preparations
Clotrimazole
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Formulary
Green

Cream 1%

Consider OTC/Self care.

 
 
Miconazole
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Formulary
Green

Cream 2%

Consider OTC/Self care.

 
Link  MHRA: Topical miconazole, including oral gel: reminder of potential for serious interactions with warfarin
 
Terbinafine
View adult BNF View SPC online View childrens BNF
Formulary
Green

Cream 1%

Consider OTC/Self care.

 
 
13.10.03  Expand sub section  Antiviral preparations
Aciclovir
View adult BNF View SPC online View childrens BNF
Formulary
Green

Cream 5%

Consider OTC/Self care.

 
 
13.10.04  Expand sub section  Parasiticidal preparations
13.10.04  Expand sub section  Scabies
13.10.04  Expand sub section  Head lice to top
13.10.04  Expand sub section  Crab lice
13.10.04  Expand sub section  Benzyl benzonate
13.10.04  Expand sub section  Carbaryl
13.10.04  Expand sub section  Dimeticone
Dimeticone (Hedrin®)
View adult BNF View SPC online View childrens BNF
Formulary
Green

Lotion 4%

Consider OTC/Self care.

 
Link  MHRA: Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarett
 
13.10.04  Expand sub section  Malathion to top
Malathion (Derbac-M®)
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Formulary
Green

Liquid 0.5%

Consider OTC/Self care.

 
Link  MHRA: Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarett
 
13.10.04  Expand sub section  Permethrin
Permethrin
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Formulary
Green

Cream 5%

Consider OTC/Self care.

 
Link  MHRA: Head lice eradication products: risk of serious burns if treated hair is exposed to open flames or other sources of ignition, eg, cigarettes
 
13.10.04  Expand sub section  Phenothrin
13.10.05  Expand sub section  Preparations for minor cuts and abrasions
13.10.05  Expand sub section  Collodion
13.10.05  Expand sub section  Skin tissue adhesive to top
13.11  Expand sub section  Skin cleansers, antiseptics, and desloughing agents
Octenisan®
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Formulary

Antimicrobial wash

 
 
13.11.01  Expand sub section  Alcohols and saline
13.11.02  Expand sub section  Chlorhexidine salts
Chlorhexidine
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Formulary
Green

Green Cleansing solution 4% (Hibiwash®)
Red Cream 1% (Hibitane Obstetric®)

 
Link  MHRA: All medical devices and medicinal products containing chlorhexidine - Risk of anaphylactic reaction due to chlorhexidine allergy
Link  MHRA: Chlorhexidine solutions: reminder of the risk of chemical burns in premature infants
 
13.11.03  Expand sub section  Cationic surfactants and soaps
13.11.04  Expand sub section  Iodine and Chlorine to top
13.11.05  Expand sub section  Phenolics
13.11.06  Expand sub section  Oxidisers, and dyes
Hydrogen Peroxide (Crystacide®)
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Formulary
Green

Cream 1%

 
 
Potassium Permanganate (Permitabs®)
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Formulary
Green

**RAG position and advisory notes currently under review. Follow local protocols. Contact your local medicines management team if futher advice is required.**

Solution tablets 400mg

Primary Care :  Potassium permanganate should always be prescribed for a named patient by a primary care prescriber, experienced in the treatment of dermatological conditions and use of potassium permanganate.
 
Secondary Care:- Potassium permanganate concentrate should always be prescribed for a named patient by a specialist in dermatology, a clinician working under the guidance of a dermatologist, or specialist tissue viability staff only.
 
Note:  A risk assessment must be completed if potassium permanganate is to be used in a patient's home.
 
Potassium permanganate is for external use only. Oral ingestion can cause fatality due to local inflammatory reactions that block the airways or cause perforations of the gastrointestinal tract, or through toxicity and organ failure. Potassium permanganate is subject to the requirements of Control of Substances Hazardous to Health including: separate storage, additional hazard labelling, and issue only to staff and patients who have been educated to understand its safe use. Accidental ingestion should be treated as a medical emergency.
 
Link  BAD and NHS England & NHS Improvement guidance on the safe use of potassium permanganate soaks
Link  BAD: Potassium permanganate solution soaks
Link  NHS Central alerting system
 
13.11.07  Expand sub section  Desloughing agents
Sterile Larvae (Maggots)
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Formulary
Red

Available to order for named patients.

 
 
13.11.07  Expand sub section  Desloughing agents
13.11.07  Expand sub section  Growth factor to top
13.12  Expand sub section  Antiperspirants
Botulinum toxin type A
View adult BNF View SPC online View childrens BNF
Formulary
Red

Powder for solution for injection
Preparations are not interchangeable.

For treatment of primary idiopathic hyperhidrosis and secondary hyperhidrosis.

- as an option for the management of severe primary idiopathic hyperhidrosis of the axillae, which does not respond to self-care strategies and topical treatment, and where the cause is NOT due to social anxiety.

- as an option for the management of severe secondary hyperhidrosis of the axillae, which does not respond to self-care strategies and topical treatment, where the cause is NOT due to social anxiety and where the primary condition has been optimally managed as far as reasonable to alleviate the hyperhidrosis.

In order to reduce the potential for antibody formation which reduces the effectiveness of treatment, inject the lowest effective dose at the longest clinically indicated interval.

 
Link  LSCMMG: Botulinum Toxin Type A for primary idiopathic hyperhidrosis and secondary hyperhidrosis NMR
Link  LSCMMG: Stepwise approach to hyperhidrosis management
 
13.13  Expand sub section  Topical circulatory preparations
13.14  Expand sub section  dermatology specials
 ....
Key
Restricted Drug Restricted Drug
Unlicensed Drug Unlicensed
click to search medicines.org.uk
Link to adult BNF
click to search medicines.org.uk
Link to children's BNF
click to search medicines.org.uk
Link to SPCs
SMC
Scottish Medicines Consortium
Cytotoxic Drug
Cytotoxic Drug
CD
Controlled Drug
High Cost Medicine
High Cost Medicine
Cancer Drugs Fund
Cancer Drugs Fund
Homecare
Homecare
CCG

ICB commissioned

NHSE
NHS England commissioned
Blueteq
Blueteq form needed
Green Low Carbon

Low carbon footprint

Amber Medium Carbon

Medium carbon footprint

Red High carbon footprint

High carbon footprint

Status Description

Green

Green: Appropriate for initiation and ongoing prescribing in both primary and secondary care. Generally, little or no routine drug monitoring is required.  

Green Restricted

Green (Restricted): Appropriate for initiation and ongoing prescribing in both primary and secondary care provided: Additional criteria specific to the medicine or device are met, or The medicine or device is used following the failure of other therapies as defined by the relevant LSCMMG pathway. Generally, little or no routine drug monitoring is required.   

Red

Red medicines: Medicine is supplied by the hospital for the duration of the treatment course. Primary care initiation or continuation of treatment is not recommended unless exceptional circumstances such as specialist GP. Red medicines are those where primary care prescribing is not recommended. These treatments should be initiated by specialists only and prescribing retained within secondary care. They require specialist knowledge, intensive monitoring, specific dose adjustments or further evaluation in use. If however, a primary care prescriber has particular specialist knowledge or experience of prescribing a particular drug for a particular patient it would not always be appropriate for them to expect to transfer that prescribing responsibility back to secondary care. There should be a specific reason and a specific risk agreement, protocol and service set up to support this. Primary care prescribers may prescribe RED medicines in exceptional circumstances to patients to ensure continuity of supply while arrangements are made to obtain ongoing supplies from secondary care.  

Amber 0

Amber level 0: Suitable for prescribing in primary care following recommendation or initiation by a specialist. Little or no specific monitoring required. Patient may need a regular review, but this would not exceed that required for other medicines routinely prescribed in primary care. Brief prescribing document or information sheet may be required. Primary care prescribers must be familiar with the drug to take on prescribing responsibility or must get the required information. When recommending or handing over care, specialists should ask primary care prescribers to take over prescribing responsibility, and should give enough information about the indication, dose, monitoring requirements, use outside product licence and any necessary dose adjustments to allow them to confidently prescribe.  

Amber 1

Amber level 1 (with shared care): Suitable for prescribing in primary care following recommendation or initiation by a specialist. Minimal monitoring required. Patient may need a regular review, but this would not exceed that required for other medicines routinely prescribed in primary care. Full prior agreement about patient’s on-going care must be reached under the shared care agreement. Primary care prescribers are advised not to take on prescribing of these medicines unless they have been adequately informed by letter of their responsibilities with regards monitoring, side effects and interactions and are happy to take on the prescribing responsibility. A copy of locally approved shared care guidelines should accompany this letter which outlines these responsibilities. Primary care prescribers should then tell secondary care of their intentions as soon as possible by letter so that arrangements can be made for the transfer of care.  

Amber 2

Amber level 2 (with shared care and enhanced service): Initiated by specialist and transferred to primary care following a successful initiation period. Significant monitoring required on an on-going basis. Full prior agreement about patient’s on-going care must be reached under the shared care agreement. Suitable for enhanced service. These medicines are considered suitable for GP prescribing following specialist initiation of therapy, as per shared care document which will be sent out with the request to prescribe, with on-going communication between the primary care prescriber and specialist. Amber Level 2 medicines require significant monitoring for which an enhanced service may be suitable. (Subject to local commissioning agreements).  

Do Not Prescribe

Do not prescribe: NOT recommended for use by the NHS in Lancashire and South Cumbria. Includes medicines that NICE has not recommended for use and terminated technology appraisals, unless there is a local need.  

Grey

Grey medicines: Medicines which have not yet been reviewed or are under the review process. GPs and specialists are recommended not to prescribe these drugs. This category includes drugs where funding has not yet been agreed.   

Multiple

Refer to local guidance.  

netFormulary