
The majority of systemic anti-cancer therapies are not listed in this formulary as they are included in either the Lancashire and South Cumbria Cancer Alliance SACT protocols or the Cancer Drugs Fund list, produced by NHSE.NHS England commissions some high cost noncancer drugs. A list of high cost drugs commissioned by NHS England can be found here |

| Avacopan Tavneos® |
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Formulary
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Hard Capsules, 10mg |
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| Pegcetacoplan Aspaveli® |
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Formulary
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Solution for infusion. Each 20 mL vial contains 1 080 mg of pegcetacoplan. |
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| Rozanolixizumab Rystiggo® |
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Formulary
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140 mg/ml solution for injection
Rozanolixizumab, as an add-on to standard treatment, can be used as an option to treat generalised myasthenia gravis in adults who test positive for anti-acetylcholine receptor (AChR) or anti-muscle-specific tyrosine kinase (MuSK) antibodies. It can only be used if:
• the condition is classified as Myasthenia Gravis Foundation of America (MGFA) class 2 to 4a
• the condition is uncontrolled after 2 or more treatments, excluding acetylcholinesterase inhibitors, and
• intravenous immunoglobulin (IVIg) or plasma exchange (PLEX) would otherwise be offered, or has been tried and stopped because of side effects or because it did not work well enough.
Rozanolixizumab will be available via the Innovative Medicines Fund (IMF) from 29th April 2026 in line with these recommendations. |
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| Ruxolitinib Jakavi® |
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Formulary
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Treatment of acute graft versus host disease that responds inadequately to corticosteroids in people 12 years and over.
There is a commercial access agreement for ruxolitinib. NHS organisations can get details on the Commercial Access and Pricing (CAP) Portal. |
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| Sirolimus Rapamune® |
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Formulary
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| Tablets 500micrograms, 1mg, 2mg The 500 microgram tablet is not bioequivalent to the 1 mg and 2 mg tablets. Multiples of 500 microgram tablets should not be used as a substitute for other tablet strengths. |
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| Sparsentan |
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Formulary
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Primary IgA nephropathy |
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| Tacrolimus |
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Formulary
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Brand name prescribing essential For prophylaxis of graft rejection Dailiport modified release oral capsules are recommended for all patients who are newly prescribed modified release tacrolimus for transplant rejection – RAG status RED for new patients See section 13.05.03 for use in dermatology. |
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| Voclosporin Lupkynis® |
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Formulary
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Capsules 7.9mg |
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